Comparative Effectiveness Review 35: Terbutaline Pump for the Prevention of Preterm Birth

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Effectiveness of Terbutaline Pump for the Prevention of Preterm Birth. A Systematic Review and Meta-Analysis

BACKGROUND Subcutaneous terbutaline (SQ terbutaline) infusion by pump is used in pregnant women as a prolonged (beyond 48-72 h) maintenance tocolytic following acute treatment of preterm contractions. The effectiveness and safety of this maintenance tocolysis have not been clearly established. We aimed to systematically evaluate the effectiveness and safety of subcutaneous (SQ) terbutaline infu...

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Uterine Contraction Monitoring, Maintenance Tocolysis, and Preterm Birth

Uterine contractions occur in runs of 1-3/hr throughout pregnancy from early in the second trimester until full term usually without consequence. Regular uterine contractions are essential in every case of preterm labor (PTL) resulting in preterm delivery at <37 weeks. It has been demonstrated that women are unable to accurately perceive the contractions associated with preterm labor while uter...

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Potentiation of the uterus-relaxing effects of β-adrenergic agonists with nifedipine: studies on rats and the human myometrium.

OBJECTIVE We investigated how progesterone and salmeterol modify the effect of nifedipine in an in vivo preterm birth model in rats, and how terbutaline and nifedipine modify the contractions of the isolated human myometrium. DESIGN Experimental animal and human myometrial studies. SAMPLE Twenty-four female Sprague-Dawley rats and 13 human uterine tissues sampled from cesarean section. ME...

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Screening to prevent spontaneous preterm birth: systematic reviews of accuracy and effectiveness literature with economic modelling.

OBJECTIVES To identify combinations of tests and treatments to predict and prevent spontaneous preterm birth. DATA SOURCES Searches were run on the following databases up to September 2005 inclusive: MEDLINE, EMBASE, DARE, the Cochrane Library (CENTRAL and Cochrane Pregnancy and Childbirth Group trials register) and MEDION. We also contacted experts including the Cochrane Pregnancy and Childb...

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Subcutaneous Terbutaline Pump for Maintenance of Tocolysis following Arrest of Acute Preterm Labor

Drs. Elliott and Morrison recently published a narrative review about the effectiveness of oral and subcutaneous maintenance of tocolytic agents following successful arrest of acute preterm labor [1]. The authors conclude that subcuta-neous terbutaline pump is beneficial and safe for maintenance of tocolysis based on all the available evidence. While the authors have provided an exhaustive list...

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تاریخ انتشار 2011